Okay, so lets back-track. It all starts with glutathione. Glutathione is the body’s most important endogenous antioxidant. Endogenous means that the body produces it (unlike antioxidants from chocolate, red wine or berries, for example). What lowers my glutathione levels? Many things can lower your glutathione levels. Anything that requires glutathione to be eliminated lowers its levels: Alcohol, Smoking, Tylenol, Pharmaceuticals, Pollutants, Heavy Metals (mercury), and Extreme Exercising. What is Glutathione? Dr Oz. 94 likes. Dr Oz Talks About Glutathione. Modern research has shown that individuals who have low levels of glutathione are. Tylenol lowers levels of glutathione in the body. Glutathione is the main anti-oxidant your body, particularly your liver, uses to remove toxins from. I prefer Motrin or Advil over Tylenol because Tylenol lowers glutathione levels in the body. Glutathione is needed to get toxins out of the body, which is especially important while sick. If I have to give Tylenol, I also give my kids glutathione gel, which I got through my holistic doctor. It’s just like a lotion that I rub on the small of their back. The dye free Motrin/Advil/Tylenol does. Sorbic Acid is FDA approved and has received its and it is CIR approved as well. Tylenol Lowers Glutathione B Mnemonic excess Folic Acid During Pregnancy Harmful? Glutathione deficiency occurs when your body is unable to produce enough glutathione to cover all the functions which this master antioxidant performs. Glutathione & The Acetaminophen (active ingredient in Tylenol) Issue: Glutathione is commonly deficient in individuals with Down Syndrome, due to the extra chromosome & overexpression of the SOD-1 gene. What depletes glutathione (GSH) levels in our bodies can be put into two categories - internal and external factors. Internal factors include the increasing need for glutathione as an important part of various processes in our bodies, such as, food for our immune system, recycling of vitamin C, vitamin E and alpha lipoic acid, repairing our DNA. New science has raised troubling concerns about the safety of acetaminophen, the main ingredient in Tylenol, which is nonetheless marketed for pain and fever relief in infants.